Lila Sciences, San Francisco, CA USA +1
Lila Sciences is building the infrastructure for autonomous science — AI systems that design experiments, run them in physical labs, and close the loop across life sciences, chemistry, and materials science. Our platform enables this to operate reliably at scale for external customers who require security, auditability, and operational rigor.
We’re hiring a Principal Engineer, Enterprise Platform to build the foundational systems that make Lila ready for the world’s largest pharmaceutical and research organizations.
Today we have the beginnings of multi-tenancy, identity and granular permissions and scopes, audit infrastructure, usage and billing. Enterprise customers require significantly more. You will drive core enterprise capabilities to production: multi-tenancy and tenant isolation, enterprise identity and permissions to support the full lifecycle of the Lila Platform, metering and billing infrastructure, audit logging, etc. You will push the frontier — building agentic AI-powered systems for self-service tenant management, intelligent customer observability, automated compliance workflows, Lila SDK, MCP, and AI-native external APIs that let customers and third-party agents interact programmatically with Lila's platform.
This is a deeply technical senior individual contributor role focused on defining and building correct, secure, and scalable platform infrastructure. This is a high-autonomy, high-impact role. We move fast, ship weekly, and expect engineers who thrive in ambiguity not ones who wait for requirements to be handed to them. You will own outcomes.
Enterprise infrastructure is foundational to making autonomous science deployable in the real world. The systems built in this role will determine how large organizations safely adopt, govern, and scale AI-driven scientific workflows across teams, data domains, and regulatory environments.
You’ll help define the platform primitives that make that possible.
$204,000—$310,000 USD
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
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Source: the Lila Sciences Greenhouse job board. We last checked this job 9 h ago. We first saw it 5 days ago. A job on a job board does not always mean that the team interviews people now. We found this job board in a public list. We did not yet compare it with the careers page of the company.
This base pay is near the median for principal infrastructure, platform and SRE jobs in the Bay Area.
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