Chai Discovery, San Francisco office
We are hiring research scientists with outlier insight who can open new avenues for the work we pursue. Our models have moved beyond protein structure prediction into real-world therapeutic engineering, and we have only just begun. We draw on the best ideas from within our domain and from across the field: pre-training large diffusion models, architecture design, post-training, and inference-time scaling.
Our team comes from physics, math, theoretical computer science, engineering, and computational biology. What we share is a record of getting hard, open-ended problems to work, and together we foster a culture of rigor, smart risk-taking, and constant collaboration. Many of us had never worked on molecules or biology before Chai.
This is the place to apply if your strongest work happened outside AI for biology, or if you aren't sure which of our research roles fits you best.
We are looking for researchers driven by impact. We index on grit, rigor and results.
We value the work product more than the pedigree, and we are happy bet on rising talent. A strong signal in any field counts, from world models or autonomous systems to top placement at IMO or Putnam.
The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.
Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs.
AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.
We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.
We value diverse perspectives and are ready to find greatness in unexpected places.
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Source: the Chai Discovery Ashby job board. We last checked this job 5 h ago. We first saw it 7 days ago. A job on a job board does not always mean that the team interviews people now. We found this job board in a public list. We did not yet compare it with the careers page of the company.
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