Chai Discovery, San Francisco office
We are hiring research scientists to improve the real-world performance of our foundation models. The work involves planning targeted data generation campaigns, designing evals that accurately measure model performance, and formulating post-training recipes aimed at making models useful for real drug discovery problems.
We prioritize simple, robust methods over intricate solutions built for narrow problems. We particularly value researchers who can formalize messy biological problems using methods from other fields.
You will work in tight loops with our pre-training researchers, research engineers and science team. Your work will ship fast and you'll see your results reach real therapeutic programs across industry.
We look for technical depth paired with interest in the underlying biology. Biological background is not required. All of the following are positive signals:
We are happy to bet on rising talent.
The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.
Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs.
AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.
We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.
We value diverse perspectives and are ready to find greatness in unexpected places.
CollinearSunnyvale, California
Pay not posted
Posted Sep 15, 2026
AchiraSan Francisco Office +1
$165K–$259K / yr
Posted Apr 29, 2026
BenchlingSan Francisco, CA
$136K–$167K / yr
Posted 9 days ago
Genesis Molecular AISan Mateo, CA +2
Pay not posted
Posted Jul 30, 2025
Isomorphic LabsLondon
Pay not posted
Posted 12 days ago
AchiraSan Francisco Office +1
$165K–$259K / yr
Posted Jun 30, 2026
Source: the Chai Discovery Ashby job board. We last checked this job 50 min ago. We first saw it 8 days ago. A job on a job board does not always mean that the team interviews people now. We found this job board in a public list. We did not yet compare it with the careers page of the company.
Funding records can have errors and can be missing. The company page has the links.
No one has reported an interview at Chai Discovery yet. Did you interview there? Add the questions.