Senior Clinical Data Manager

The role

The Senior Manager, Clinical Data Management serves as the Data Management lead for assigned clinical trials and is responsible for the planning, oversight, execution, and delivery of data management activities from study startup through database lock and study closeout. The role provides sponsor oversight of outsourced data management activities, ensures high-quality and inspection-ready clinical data, and collaborates with cross-functional stakeholders to support trial execution, regulatory compliance, and clinical development objectives.

Posted pay

$145K–$217K

a year

Compared with similar jobs

This base pay is near the median for senior software engineering jobs in other US places.

Median: $188K a year
Other jobs in the group: 1,833

We compare the middle of each posted range. This is base pay as posted. The group does not include this job.

Location

Boston, MA +1

Work type

Not given

Level

Senior, manager

Experience

5+ years

Posted

Sep 18, 2026

Last check

7 h ago

Job type

Software engineering

The role

What you need

Bachelor's degree in Computer Science, Life Sciences, Mathematics, Health Sciences, or related field
5+ years of Clinical Data Management experience within the biotechnology, pharmaceutical, or CRO industry
Experience leading Data Management activities for clinical trials in a regulated environment
Experience managing outsourced Data Management activities and providing vendor oversight
Experience managing clinical systems (incl. IRT/ eCOA) configurations and implementations, enhancements, integrations, and technology vendors;
Experience leading User Acceptance Testing (UAT)
Experience supporting database build, data cleaning, external data integrations, medical coding, database lock, and submission readiness activities
Experience working within global clinical development organizations
Experience supporting audits, inspections, and inspection-readiness activities preferred
Experience using electronic data capture (EDC) platforms and clinical data technologies
Oncology clinical development experience preferred
Strong knowledge of Clinical Data Management processes and the clinical trial data lifecycle
Strong knowledge of ICH-GCP, FDA regulations, EU Clinical Trial Regulation (CTR), data integrity principles, and other applicable regulatory requirements
Knowledge of CDISC standards, including CDASH and SDTM, and associated clinical data requirements
Proficiency with EDC systems, IRT, eCOA, and related clinical technologies
Knowledge of medical coding dictionaries, including MedDRA and WHODrug
Familiarity with data visualization, analytics, and reporting tools
Strong understanding of risk-based quality management and critical-to-quality (CtQ) principles
Strong vendor management and sponsor oversight capabilities
Strong project management, organizational, and prioritization skills
Excellent collaboration skills with cross-functional stakeholders, including Biostatistics, Statistical Programming, Pharmacovigilance, Clinical Operations, and Regulatory Affairs
Strong analytical thinking, problem-solving, and decision-making capabilities
Excellent written and verbal communication skills

We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Senior Clinical Data Manager

The role

Senior Clinical Data Manager

The role

What you need

Pay and benefits

About Tango Therapeutics

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