Why This Role Matters Every architectural decision here has a direct line to patients getting care faster. The systems you design will determine whether our agents can be trusted with clinical workflows at enterprise scale — and whether a small, sharp team can keep shipping quickly as the platform grows. You will set technical direction at the stage where it compounds the most.
100ms is building AI agents that automate complex patient access workflows in U.S. healthcare — starting with benefits verification, prior authorisation, and referral intake in speciality pharmacy. Our platform combines LLM-based agents, deep healthcare domain expertise, and operational infrastructure to help care teams move faster and get patients on treatment sooner.
Role Summary We are looking for a Software Engineer Architect to own the technical architecture of our AI agents platform as it scales. In healthcare, accuracy and trust are everything — our systems make phone calls to payers, handle Protected Health Information, and operate inside real clinical workflows, so the architecture underneath them has to be reliable, observable, secure, and fast to evolve.
This is a hands-on, deeply technical role, not a pure design-review position. You will define how our services, data, and agent pipelines fit together; make the build-vs-buy and technology choices that shape the next three years of the platform; write code on the hardest problems; and raise the engineering bar across the team.
You will work directly with the founders, product, platform/infrastructure, and security teams, and your decisions will be informed by real customer and clinical workflows.
$170K–$270K / yr
Posted May 11, 2026
Citizen HealthSan Francisco
$150K–$300K / yr
Posted May 20, 2026
MachinifyRemote - US
Pay not posted
Posted Feb 24, 2026
Develop HealthSan Francisco Bay Area
$200K–$250K / yr
Posted 23 days ago
Source: the 100MS Lever job board. We last checked this job 5 h ago. We first saw it 8 days ago. A job on a job board does not always mean that the team interviews people now. We found this job board in a public list. We did not yet compare it with the careers page of the company.
Cohere HealthHyderabad, Telangana, India +1
Pay not posted
Posted Jun 4, 2026
Develop HealthSan Francisco Bay Area
$200K–$250K / yr
Posted 23 days ago
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