Scientist/Sr. Scientist, Pre-clinical Pharmacology (Neuroscience & Metabolism)
Manifold Bio, Boston +1
The role
We are seeking a PhD-level scientist to run preclinical pharmacology and target validation studies for our neuroscience and metabolic programs, with a focus on siRNA and oligonucleotide therapeutics. This is a hands-on lab role. You will execute vivo studies, run the downstream assays that show whether a target is engaged and a therapeutic is working, and turn that data into clear answers for the team. Our work centers on neurodegenerative diseases, obesity and cardiometabolic disease across adipose, liver, and heart, with some programs touching the neural regulation of energy balance